On Monday, Telomir Prescribed drugs, Inc. TELO introduced preclinical findings highlighting the copper-binding potential of its lead compound, Telomir-1, as a promising remedy for Wilson’s illness and associated problems. The compound displays a binding affinity for copper ions, enabling exact regulation of copper metabolism and interacting with important ions resembling copper, iron, and zinc, the corporate mentioned.
Current preclinical research by Recipharm and Sensible Assays reveal Telomir-1’s sturdy copper-binding affinity, enabling exact regulation of copper metabolism and interplay with important ions.
In accordance with the corporate, these findings place Telomir-1 as a possible breakthrough remedy for Wilson’s illness, a uncommon dysfunction attributable to ATP7B mutations resulting in poisonous copper buildup in important organs.
Providing a safer different to present remedies, which have vital unintended effects and require lifelong adherence, Telomir-1 targets the illness’s root trigger and will qualify for orphan drug designation.
Telomir can be advancing Telomir-1’s therapeutic potential in associated areas, together with Kind 2 diabetes and age-related ailments.
The corporate is optimizing GMP-grade manufacturing for IND-enabling research scheduled for second quarter of 2025, with an IND submission deliberate for the fourth quarter and first-in-human medical trials anticipated by mid-2026. Efforts additionally embrace securing an INAD for pets and exploring Telomir-1’s twin purposes in human and veterinary medication.
Consistent with its moral practices, Telomir discontinued its osteoarthritis examine in canines after the protection section on account of considerations over inducing the situation. The corporate is now collaborating with a veterinary establishment to design a examine utilizing aged canines naturally affected by osteoarthritis, advancing its INAD utility for pets.
“As we glance to 2025, Telomir stays devoted to its mission,” mentioned Erez Aminov, Chairman and CEO. “We’re happy to have secured extra financing at a 20% premium with no warrants, offering the assets wanted to proceed advancing Telomir-1’s growth whereas creating worth for our shareholders.”
Value Motion: TELO shares closed 14.10% larger at $5.18 on Friday.
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